Symbiotic macrophage-glioma cell interactions reveal synthetic lethality in PTEN null glioma

Heterotypic interactions across diverse cell types can enable tumor progression and hold the potential to expand therapeutic interventions. Here, combined profiling and functional studies of glioma cells in glioblastoma multiforme (GBM) models establish that PTEN deficiency activates YAP1, which dir...

詳細記述

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書誌詳細
出版年:Cancer Cell
主要な著者: Chen, Peiwen, Zhao, Di, Li, Jun, Liang, Xin, Li, Jiexi, Chang, Andrew, Henry, Verlene K., Lan, Zhengdao, Spring, Denise J., Rao, Ganesh, Wang, Y. Alan, DePinho, Ronald A.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561349/
https://ncbi.nlm.nih.gov/pubmed/31185211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.05.003
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