Aneuploidy drives lethal progression in prostate cancer

Aneuploidy, defined as chromosome gains and losses, is a hallmark of cancer. However, compared with other tumor types, extensive aneuploidy is relatively rare in prostate cancer. Thus, whether numerical chromosome aberrations dictate disease progression in prostate cancer patients is not known. Here...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Stopsack, Konrad H., Whittaker, Charles A., Gerke, Travis A., Loda, Massimo, Kantoff, Philip W., Mucci, Lorelei A., Amon, Angelika
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561291/
https://ncbi.nlm.nih.gov/pubmed/31085648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902645116
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