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Aneuploidy drives lethal progression in prostate cancer

Aneuploidy, defined as chromosome gains and losses, is a hallmark of cancer. However, compared with other tumor types, extensive aneuploidy is relatively rare in prostate cancer. Thus, whether numerical chromosome aberrations dictate disease progression in prostate cancer patients is not known. Here...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Stopsack, Konrad H., Whittaker, Charles A., Gerke, Travis A., Loda, Massimo, Kantoff, Philip W., Mucci, Lorelei A., Amon, Angelika
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561291/
https://ncbi.nlm.nih.gov/pubmed/31085648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902645116
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