Aneuploidy drives lethal progression in prostate cancer

Aneuploidy, defined as chromosome gains and losses, is a hallmark of cancer. However, compared with other tumor types, extensive aneuploidy is relatively rare in prostate cancer. Thus, whether numerical chromosome aberrations dictate disease progression in prostate cancer patients is not known. Here...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Stopsack, Konrad H., Whittaker, Charles A., Gerke, Travis A., Loda, Massimo, Kantoff, Philip W., Mucci, Lorelei A., Amon, Angelika
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561291/
https://ncbi.nlm.nih.gov/pubmed/31085648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902645116
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