Low expression of the androgen-induced tumor suppressor gene PLZF and lethal prostate cancer

BACKGROUND: 4–9% of prostate cancers harbor homozygous deletions of the androgen-induced tumor suppressor gene, PLZF (ZBTB16). PLZF loss induces an in vitro phenotype of castration resistance and enzalutamide resistance. The association of low expression of PLZF and clinical outcomes is unclear. MET...

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Detaylı Bibliyografya
Yayımlandı:Cancer Epidemiol Biomarkers Prev
Asıl Yazarlar: Stopsack, Konrad H., Gerke, Travis, Tyekucheva, Svitlana, Mazzu, Ying Z., Lee, Gwo-Shu Mary, Chakraborty, Goutam, Abida, Wassim, Mucci, Lorelei A., Kantoff, Philip W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532645/
https://ncbi.nlm.nih.gov/pubmed/30602500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-18-1014
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