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Low expression of the androgen-induced tumor suppressor gene PLZF and lethal prostate cancer
BACKGROUND: 4–9% of prostate cancers harbor homozygous deletions of the androgen-induced tumor suppressor gene, PLZF (ZBTB16). PLZF loss induces an in vitro phenotype of castration resistance and enzalutamide resistance. The association of low expression of PLZF and clinical outcomes is unclear. MET...
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| Publicado no: | Cancer Epidemiol Biomarkers Prev |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6532645/ https://ncbi.nlm.nih.gov/pubmed/30602500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-18-1014 |
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