Aneuploidy drives lethal progression in prostate cancer

Aneuploidy, defined as chromosome gains and losses, is a hallmark of cancer. However, compared with other tumor types, extensive aneuploidy is relatively rare in prostate cancer. Thus, whether numerical chromosome aberrations dictate disease progression in prostate cancer patients is not known. Here...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Stopsack, Konrad H., Whittaker, Charles A., Gerke, Travis A., Loda, Massimo, Kantoff, Philip W., Mucci, Lorelei A., Amon, Angelika
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2019
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561291/
https://ncbi.nlm.nih.gov/pubmed/31085648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902645116
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