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Hatchet ribozyme structure and implications for cleavage mechanism
Small self-cleaving ribozymes catalyze site-specific cleavage of their own phosphodiester backbone with implications for viral genome replication, pre-mRNA processing, and alternative splicing. We report on the 2.1-Å crystal structure of the hatchet ribozyme product, which adopts a compact pseudosym...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6561176/ https://ncbi.nlm.nih.gov/pubmed/31088965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902413116 |
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