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Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage

The field of small self-cleaving nucleolytic ribozymes has been invigorated by the recent discovery of the twister, twister-sister, pistol and hatchet ribozymes. We report on the crystal structure of the env25 pistol ribozyme, which adopts a compact tertiary architecture stabilized by an embedded ps...

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Publicado en:Nat Chem Biol
Main Authors: Ren, Aiming, Vušurović, Nikola, Gebetsberger, Jennifer, Gao, Pu, Juen, Michael, Kreutz, Christoph, Micura, Ronald, Patel, Dinshaw J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990474/
https://ncbi.nlm.nih.gov/pubmed/27398999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2125
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