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Pseudoknot Formation Seeds the Twister Ribozyme Cleavage Reaction Coordinate

The twister RNA is a recently discovered nucleolytic ribozyme that is present in both bacteria and eukarya. While its biological role remains unclear, crystal structure analyses and biochemical approaches have revealed critical features of its catalytic mechanism. Here, we set out to explore dynamic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Vušurović, Nikola, Altman, Roger B., Terry, Daniel S., Micura, Ronald, Blanchard, Scott C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697751/
https://ncbi.nlm.nih.gov/pubmed/28598157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01549
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