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Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Here we report on the crystal structure and cleavage assays of a four-way junctional twister-sister self-cleaving ribozyme. Notably, 11 conserved spatially separated loop nucleotides are brought into close proximity at the ribozyme core through long-range interactions mediated by hydrated Mg(2+) cat...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660989/ https://ncbi.nlm.nih.gov/pubmed/29081514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01276-y |
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