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Structure-based mechanistic insights into catalysis by small self-cleaving ribozymes

Small self-cleaving ribozymes are widely distributed in nature and are essential for rolling-circle-based replication of satellite and pathogenic RNAs. Earlier structure-function studies on the hammerhead, hairpin, glmS, hepatitis delta virus and Varkud satellite ribozymes have provided insights int...

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Veröffentlicht in:Curr Opin Chem Biol
Hauptverfasser: Ren, Aiming, Micura, Ronald, Patel, Dinshaw J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955703/
https://ncbi.nlm.nih.gov/pubmed/29107885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2017.09.017
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