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Structural diversity of self-cleaving ribozymes

In vitro selection was used to isolate Mg(2+)-dependent self-cleaving ribozymes from random sequence. Characterization of representative clones revealed the emergence of at least 12 classes of ribozymes that adopt distinct secondary structure motifs. Only one class corresponds to a previously known...

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Bibliografiske detaljer
Main Authors: Tang, Jin, Breaker, Ronald R.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18511/
https://ncbi.nlm.nih.gov/pubmed/10823936
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