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Structural diversity of self-cleaving ribozymes

In vitro selection was used to isolate Mg(2+)-dependent self-cleaving ribozymes from random sequence. Characterization of representative clones revealed the emergence of at least 12 classes of ribozymes that adopt distinct secondary structure motifs. Only one class corresponds to a previously known...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Tang, Jin, Breaker, Ronald R.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 2000
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18511/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823936/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.11.5784
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