Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course

BACKGROUND: Multiple Sclerosis (MS) results from genetic predisposition and environmental variables, including elevated Body Mass Index (BMI) in early life. This study addresses the effect of BMI on the epigenome of monocytes and disease course in MS. METHODS: Fifty-four therapy-naive Relapsing Remi...

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Detaylı Bibliyografya
Yayımlandı:EBioMedicine
Asıl Yazarlar: Castro, Kamilah, Ntranos, Achilles, Amatruda, Mario, Petracca, Maria, Kosa, Peter, Chen, Emily Y., Morstein, Johannes, Trauner, Dirk, Watson, Corey T., Kiebish, Michael A., Bielekova, Bibiana, Inglese, Matilde, Katz Sand, Ilana, Casaccia, Patrizia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2019
Konular:
Research paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557766/
https://ncbi.nlm.nih.gov/pubmed/30981648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.087
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