Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course

BACKGROUND: Multiple Sclerosis (MS) results from genetic predisposition and environmental variables, including elevated Body Mass Index (BMI) in early life. This study addresses the effect of BMI on the epigenome of monocytes and disease course in MS. METHODS: Fifty-four therapy-naive Relapsing Remi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EBioMedicine
Hlavní autoři: Castro, Kamilah, Ntranos, Achilles, Amatruda, Mario, Petracca, Maria, Kosa, Peter, Chen, Emily Y., Morstein, Johannes, Trauner, Dirk, Watson, Corey T., Kiebish, Michael A., Bielekova, Bibiana, Inglese, Matilde, Katz Sand, Ilana, Casaccia, Patrizia
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557766/
https://ncbi.nlm.nih.gov/pubmed/30981648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.087
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky