Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course

BACKGROUND: Multiple Sclerosis (MS) results from genetic predisposition and environmental variables, including elevated Body Mass Index (BMI) in early life. This study addresses the effect of BMI on the epigenome of monocytes and disease course in MS. METHODS: Fifty-four therapy-naive Relapsing Remi...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Castro, Kamilah, Ntranos, Achilles, Amatruda, Mario, Petracca, Maria, Kosa, Peter, Chen, Emily Y., Morstein, Johannes, Trauner, Dirk, Watson, Corey T., Kiebish, Michael A., Bielekova, Bibiana, Inglese, Matilde, Katz Sand, Ilana, Casaccia, Patrizia
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557766/
https://ncbi.nlm.nih.gov/pubmed/30981648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.087
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