Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics

Axonal damage is a prominent cause of disability and yet its pathogenesis is incompletely understood. Using a xenogeneic system, here we define the bioenergetic changes induced in rat neurons by exposure to cerebrospinal fluid samples from patients with multiple sclerosis compared to control subject...

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Bibliografiska uppgifter
Huvudupphovsmän: Vidaurre, Oscar G., Haines, Jeffery D., Katz Sand, Ilana, Adula, Kadidia P., Huynh, Jimmy L., McGraw, Corey A., Zhang, Fan, Varghese, Merina, Sotirchos, Elias, Bhargava, Pavan, Bandaru, Veera Venkata Ratnam, Pasinetti, Giulio, Zhang, Weijia, Inglese, Matilde, Calabresi, Peter A., Wu, Gang, Miller, Aaron E., Haughey, Norman J., Lublin, Fred D., Casaccia, Patrizia
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164163/
https://ncbi.nlm.nih.gov/pubmed/24893707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu139
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