Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics

Axonal damage is a prominent cause of disability and yet its pathogenesis is incompletely understood. Using a xenogeneic system, here we define the bioenergetic changes induced in rat neurons by exposure to cerebrospinal fluid samples from patients with multiple sclerosis compared to control subject...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vidaurre, Oscar G., Haines, Jeffery D., Katz Sand, Ilana, Adula, Kadidia P., Huynh, Jimmy L., McGraw, Corey A., Zhang, Fan, Varghese, Merina, Sotirchos, Elias, Bhargava, Pavan, Bandaru, Veera Venkata Ratnam, Pasinetti, Giulio, Zhang, Weijia, Inglese, Matilde, Calabresi, Peter A., Wu, Gang, Miller, Aaron E., Haughey, Norman J., Lublin, Fred D., Casaccia, Patrizia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164163/
https://ncbi.nlm.nih.gov/pubmed/24893707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu139
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