Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics

Axonal damage is a prominent cause of disability and yet its pathogenesis is incompletely understood. Using a xenogeneic system, here we define the bioenergetic changes induced in rat neurons by exposure to cerebrospinal fluid samples from patients with multiple sclerosis compared to control subject...

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Detalhes bibliográficos
Main Authors: Vidaurre, Oscar G., Haines, Jeffery D., Katz Sand, Ilana, Adula, Kadidia P., Huynh, Jimmy L., McGraw, Corey A., Zhang, Fan, Varghese, Merina, Sotirchos, Elias, Bhargava, Pavan, Bandaru, Veera Venkata Ratnam, Pasinetti, Giulio, Zhang, Weijia, Inglese, Matilde, Calabresi, Peter A., Wu, Gang, Miller, Aaron E., Haughey, Norman J., Lublin, Fred D., Casaccia, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164163/
https://ncbi.nlm.nih.gov/pubmed/24893707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu139
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