The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice

Hepatitis B virus (HBV) infection is a major health burden worldwide with 240 million chronically infected individuals. Nucleos(t)ide analogs and interferons are the current standards of care due to their suppression of HBV replication, but the treatments rarely eradicate HBV from individuals. Simil...

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Veröffentlicht in:PLoS One
Hauptverfasser: Gallay, Philippe, Ure, Daren, Bobardt, Michael, Chatterji, Udayan, Ou, James, Trepanier, Daniel, Foster, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557616/
https://ncbi.nlm.nih.gov/pubmed/31181107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217433
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