A carregar...

Structurally distinct cyclosporin and sanglifehrin analogs CRV431 and NV556 suppress established HCV infection in humanized-liver mice

We previously reported that the non-immunosuppressive cyclophilin inhibitors (CypIs)—cyclosporin A analog CRV431 and sanglifehrin analog NV556—efficiently inhibit HCV replication in vitro. In this study, we asked whether they can also reduce HCV replication in vivo. We found that a single oral admin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bobardt, Michael, Hansson, Magnus Joakim, Mayo, Patrick, Ure, Daren, Foster, Robert, Gallay, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413547/
https://ncbi.nlm.nih.gov/pubmed/32764799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237236
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!