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The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice

Hepatitis B virus (HBV) infection is a major health burden worldwide with 240 million chronically infected individuals. Nucleos(t)ide analogs and interferons are the current standards of care due to their suppression of HBV replication, but the treatments rarely eradicate HBV from individuals. Simil...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gallay, Philippe, Ure, Daren, Bobardt, Michael, Chatterji, Udayan, Ou, James, Trepanier, Daniel, Foster, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557616/
https://ncbi.nlm.nih.gov/pubmed/31181107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217433
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