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The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice

Hepatitis B virus (HBV) infection is a major health burden worldwide with 240 million chronically infected individuals. Nucleos(t)ide analogs and interferons are the current standards of care due to their suppression of HBV replication, but the treatments rarely eradicate HBV from individuals. Simil...

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書目詳細資料
發表在:PLoS One
Main Authors: Gallay, Philippe, Ure, Daren, Bobardt, Michael, Chatterji, Udayan, Ou, James, Trepanier, Daniel, Foster, Robert
格式: Artigo
語言:Inglês
出版: Public Library of Science 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557616/
https://ncbi.nlm.nih.gov/pubmed/31181107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217433
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