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The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice

Hepatitis B virus (HBV) infection is a major health burden worldwide with 240 million chronically infected individuals. Nucleos(t)ide analogs and interferons are the current standards of care due to their suppression of HBV replication, but the treatments rarely eradicate HBV from individuals. Simil...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Gallay, Philippe, Ure, Daren, Bobardt, Michael, Chatterji, Udayan, Ou, James, Trepanier, Daniel, Foster, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557616/
https://ncbi.nlm.nih.gov/pubmed/31181107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217433
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