OR34-2 SREBP1 Drives KRT80-Dependent Cytoskeletal Changes and Invasive Behaviour in Endocrine-Resistant ERα Breast Cancer

About one third of oestrogen receptor alpha breast cancer (ERα BC) patients progress to invasive metastatic disease despite targeted endocrine therapies(1). Our previous study showed how breast cancer cells developing resistance to aromatase inhibitors (AI) endogenously trigger cholesterol biosynthe...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Perone, Ylenia, Rodríguez Meira, Alba, Farruggia, Aaron, Győrffy, Balázs, Ion, Charlotte, Pruneri, Giancarlo, Lim, Adrian, Calvo, Fernando, Magnani, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Tumor Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555066/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR34-2
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