OR34-2 SREBP1 Drives KRT80-Dependent Cytoskeletal Changes and Invasive Behaviour in Endocrine-Resistant ERα Breast Cancer

About one third of oestrogen receptor alpha breast cancer (ERα BC) patients progress to invasive metastatic disease despite targeted endocrine therapies(1). Our previous study showed how breast cancer cells developing resistance to aromatase inhibitors (AI) endogenously trigger cholesterol biosynthe...

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Dettagli Bibliografici
Pubblicato in:J Endocr Soc
Autori principali: Perone, Ylenia, Rodríguez Meira, Alba, Farruggia, Aaron, Győrffy, Balázs, Ion, Charlotte, Pruneri, Giancarlo, Lim, Adrian, Calvo, Fernando, Magnani, Luca
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2019
Soggetti:
Tumor Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555066/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR34-2
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