SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer

Approximately 30% of ERα breast cancer patients relapse with metastatic disease following adjuvant endocrine therapies. The connection between acquisition of drug resistance and invasive potential is poorly understood. In this study, we demonstrate that the type II keratin topological associating do...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Perone, Ylenia, Farrugia, Aaron J., Rodríguez-Meira, Alba, Győrffy, Balázs, Ion, Charlotte, Uggetti, Andrea, Chronopoulos, Antonios, Marrazzo, Pasquale, Faronato, Monica, Shousha, Sami, Davies, Claire, Steel, Jennifer H., Patel, Naina, del Rio Hernandez, Armando, Coombes, Charles, Pruneri, Giancarlo, Lim, Adrian, Calvo, Fernando, Magnani, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509342/
https://ncbi.nlm.nih.gov/pubmed/31073170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09676-y
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