OR34-2 SREBP1 Drives KRT80-Dependent Cytoskeletal Changes and Invasive Behaviour in Endocrine-Resistant ERα Breast Cancer

About one third of oestrogen receptor alpha breast cancer (ERα BC) patients progress to invasive metastatic disease despite targeted endocrine therapies(1). Our previous study showed how breast cancer cells developing resistance to aromatase inhibitors (AI) endogenously trigger cholesterol biosynthe...

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Publicat a:J Endocr Soc
Autors principals: Perone, Ylenia, Rodríguez Meira, Alba, Farruggia, Aaron, Győrffy, Balázs, Ion, Charlotte, Pruneri, Giancarlo, Lim, Adrian, Calvo, Fernando, Magnani, Luca
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Tumor Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555066/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR34-2
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