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Engineering of Chimeric Polyketide Synthases Using SYNZIP Docking Domains

Engineering of assembly line polyketide synthases (PKSs) to produce novel bioactive compounds has been a goal for over 20 years. The apparent modularity of PKSs has inspired many engineering attempts in which entire modules or single domains were exchanged. In recent years, it has become evident tha...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Klaus, Maja, D’Souza, Alicia D., Nivina, Aleksandra, Khosla, Chaitan, Grininger, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554747/
https://ncbi.nlm.nih.gov/pubmed/30682239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b01060
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