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Engineering the acyltransferase substrate specificity of assembly line polyketide synthases
Polyketide natural products act as a broad range of therapeutics, including antibiotics, immunosuppressants and anti-cancer agents. This therapeutic diversity stems from the structural diversity of these small molecules, many of which are produced in an assembly line manner by modular polyketide syn...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Royal Society
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971720/ https://ncbi.nlm.nih.gov/pubmed/23720536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2013.0297 |
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