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Computational identification and analysis of orphan assembly-line polyketide synthases

The increasing availability of DNA sequence data offers an opportunity for identifying new assembly-line polyketide synthases (PKSs) that produce biologically active natural products. We developed an automated method to extract and consolidate all multimodular PKS sequences (including hybrid PKS/non...

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Autors principals: O’Brien, Robert V, Davis, Ronald W, Khosla, Chaitan, Hillenmeyer, Maureen E
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028714/
https://ncbi.nlm.nih.gov/pubmed/24301183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2013.125
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