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GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification
Assembly-line polyketide synthases (PKSs) are large and complex enzymatic machineries with a multimodular architecture, typically encoded in bacterial genomes by biosynthetic gene clusters. Their modularity has led to an astounding diversity of biosynthesized molecules, many with medical relevance....
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8256042/ https://ncbi.nlm.nih.gov/pubmed/34162709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100751118 |
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