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GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification

Assembly-line polyketide synthases (PKSs) are large and complex enzymatic machineries with a multimodular architecture, typically encoded in bacterial genomes by biosynthetic gene clusters. Their modularity has led to an astounding diversity of biosynthesized molecules, many with medical relevance....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nivina, Aleksandra, Herrera Paredes, Sur, Fraser, Hunter B., Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256042/
https://ncbi.nlm.nih.gov/pubmed/34162709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100751118
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