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Engineering of Chimeric Polyketide Synthases Using SYNZIP Docking Domains

Engineering of assembly line polyketide synthases (PKSs) to produce novel bioactive compounds has been a goal for over 20 years. The apparent modularity of PKSs has inspired many engineering attempts in which entire modules or single domains were exchanged. In recent years, it has become evident tha...

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Bibliografische gegevens
Gepubliceerd in:ACS Chem Biol
Hoofdauteurs: Klaus, Maja, D’Souza, Alicia D., Nivina, Aleksandra, Khosla, Chaitan, Grininger, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554747/
https://ncbi.nlm.nih.gov/pubmed/30682239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b01060
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