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Engineering of Chimeric Polyketide Synthases Using SYNZIP Docking Domains
Engineering of assembly line polyketide synthases (PKSs) to produce novel bioactive compounds has been a goal for over 20 years. The apparent modularity of PKSs has inspired many engineering attempts in which entire modules or single domains were exchanged. In recent years, it has become evident tha...
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| Pubblicato in: | ACS Chem Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6554747/ https://ncbi.nlm.nih.gov/pubmed/30682239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b01060 |
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