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Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma

Clinical success of autologous CD19-directed chimeric antigen receptor T cells (CAR Ts) in acute lymphoblastic leukemia and non-Hodgkin lymphoma suggests that CAR Ts may be a promising therapy for hematological malignancies, including multiple myeloma. However, autologous CAR T therapies have limita...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Sommer, Cesar, Boldajipour, Bijan, Kuo, Tracy C., Bentley, Trevor, Sutton, Janette, Chen, Amy, Geng, Tao, Dong, Holly, Galetto, Roman, Valton, Julien, Pertel, Thomas, Juillerat, Alexandre, Gariboldi, Annabelle, Pascua, Edward, Brown, Colleen, Chin, Sherman M., Sai, Tao, Ni, Yajin, Duchateau, Philippe, Smith, Julianne, Rajpal, Arvind, Van Blarcom, Thomas, Chaparro-Riggers, Javier, Sasu, Barbra J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554542/
https://ncbi.nlm.nih.gov/pubmed/31005597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.04.001
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