Direct control of CAR T cells through small molecule-regulated antibodies

Antibody-based therapeutics have experienced a rapid growth in recent years and are now utilized in various modalities spanning from conventional antibodies, antibody-drug conjugates, bispecific antibodies to chimeric antigen receptor (CAR) T cells. Many next generation antibody therapeutics achieve...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Park, Spencer, Pascua, Edward, Lindquist, Kevin C., Kimberlin, Christopher, Deng, Xiaodi, Mak, Yvonne S. L., Melton, Zea, Johnson, Theodore O., Lin, Regina, Boldajipour, Bijan, Abraham, Robert T., Pons, Jaume, Sasu, Barbra Johnson, Van Blarcom, Thomas J., Chaparro-Riggers, Javier
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846603/
https://ncbi.nlm.nih.gov/pubmed/33514714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20671-6
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