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Alcohol exposure alters pre-mRNA splicing of antiapoptotic Mcl-1L isoform and induces apoptosis in neural progenitors and immature neurons

Alternative splicing and expression of splice variants of genes in the brain may lead to the modulation of protein functions, which may ultimately influence behaviors associated with alcohol dependence and neurotoxicity. We recently showed that ethanol exposure can lead to pre-mRNA missplicing of Mc...

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Publicat a:Cell Death Dis
Autors principals: Donadoni, Martina, Cicalese, Stephanie, Sarkar, Dipak K., Chang, Sulie L., Sariyer, Ilker Kudret
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554352/
https://ncbi.nlm.nih.gov/pubmed/31171771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1673-3
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