Загрузка...
Chemical perturbation of Mcl-1 pre-mRNA splicing to induce apoptosis in cancer cells
The myeloid cell leukemia-1 (MCL1) gene encodes antiapoptotic Mcl-1(L) and proapoptotic Mcl-1(S) proteins. In cancer, the Mcl-1(L)/Mcl-1(S) ratio is very high, accounting for the antiapoptotic nature of cancer cells. As such, reducing this ratio can render the cancer cells prone to apoptosis. The Mc...
Сохранить в:
| Главные авторы: | , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3657302/ https://ncbi.nlm.nih.gov/pubmed/23485022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300602j |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|