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Regulation of Human Neurotropic JC Virus Replication by Alternative Splicing Factor SF2/ASF in Glial Cells

BACKGROUND: The human neurotropic virus, JC virus (JCV), is the etiologic agent of the fatal demyelinating disease of the central nervous system, Progressive Multifocal Leukoencephlopathy (PML) that is seen primarily in immunodeficient individuals. Productive infection of JCV occurs only in glial ce...

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Autors principals: Sariyer, Ilker Kudret, Khalili, Kamel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031499/
https://ncbi.nlm.nih.gov/pubmed/21297941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014630
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