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Alcohol exposure alters pre-mRNA splicing of antiapoptotic Mcl-1L isoform and induces apoptosis in neural progenitors and immature neurons

Alternative splicing and expression of splice variants of genes in the brain may lead to the modulation of protein functions, which may ultimately influence behaviors associated with alcohol dependence and neurotoxicity. We recently showed that ethanol exposure can lead to pre-mRNA missplicing of Mc...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Donadoni, Martina, Cicalese, Stephanie, Sarkar, Dipak K., Chang, Sulie L., Sariyer, Ilker Kudret
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554352/
https://ncbi.nlm.nih.gov/pubmed/31171771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1673-3
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