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Alcohol exposure alters pre-mRNA splicing of antiapoptotic Mcl-1L isoform and induces apoptosis in neural progenitors and immature neurons

Alternative splicing and expression of splice variants of genes in the brain may lead to the modulation of protein functions, which may ultimately influence behaviors associated with alcohol dependence and neurotoxicity. We recently showed that ethanol exposure can lead to pre-mRNA missplicing of Mc...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Donadoni, Martina, Cicalese, Stephanie, Sarkar, Dipak K., Chang, Sulie L., Sariyer, Ilker Kudret
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554352/
https://ncbi.nlm.nih.gov/pubmed/31171771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1673-3
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