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Alcohol-mediated missplicing of Mcl-1 pre-mRNA is involved in neurotoxicity

BACKGROUND: Heavy and chronic ethanol (EtOH) exposure can cause significant structural and functional damage to the adult brain. The most devastating consequence of EtOH exposure is the neurotoxicity associated with the depletion of neurons. Regulation of splice variants in the brain can modulate pr...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Sariyer, Rahsan, De Simone, Francesca I., Donadoni, Martina, Hoek, Jan B, Chang, Sulie L., Sariyer, Ilker Kudret
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626641/
https://ncbi.nlm.nih.gov/pubmed/28800142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13474
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