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Alcohol-mediated missplicing of Mcl-1 pre-mRNA is involved in neurotoxicity

BACKGROUND: Heavy and chronic ethanol (EtOH) exposure can cause significant structural and functional damage to the adult brain. The most devastating consequence of EtOH exposure is the neurotoxicity associated with the depletion of neurons. Regulation of splice variants in the brain can modulate pr...

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Dettagli Bibliografici
Pubblicato in:Alcohol Clin Exp Res
Autori principali: Sariyer, Rahsan, De Simone, Francesca I., Donadoni, Martina, Hoek, Jan B, Chang, Sulie L., Sariyer, Ilker Kudret
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626641/
https://ncbi.nlm.nih.gov/pubmed/28800142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13474
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