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Alcohol-mediated missplicing of Mcl-1 pre-mRNA is involved in neurotoxicity
BACKGROUND: Heavy and chronic ethanol (EtOH) exposure can cause significant structural and functional damage to the adult brain. The most devastating consequence of EtOH exposure is the neurotoxicity associated with the depletion of neurons. Regulation of splice variants in the brain can modulate pr...
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| Publié dans: | Alcohol Clin Exp Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5626641/ https://ncbi.nlm.nih.gov/pubmed/28800142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13474 |
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