Alcohol-mediated missplicing of Mcl-1 pre-mRNA is involved in neurotoxicity

BACKGROUND: Heavy and chronic ethanol (EtOH) exposure can cause significant structural and functional damage to the adult brain. The most devastating consequence of EtOH exposure is the neurotoxicity associated with the depletion of neurons. Regulation of splice variants in the brain can modulate pr...

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Udgivet i:Alcohol Clin Exp Res
Main Authors: Sariyer, Rahsan, De Simone, Francesca I., Donadoni, Martina, Hoek, Jan B, Chang, Sulie L., Sariyer, Ilker Kudret
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626641/
https://ncbi.nlm.nih.gov/pubmed/28800142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13474
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