Beyond Blood Smears: Qualification of Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections

18S rRNA is a biomarker that provides an alternative to thick blood smears in controlled human malaria infection (CHMI) trials. We reviewed data from CHMI trials at non-endemic sites that used blood smears and Plasmodium 18S rRNA/rDNA biomarker nucleic acid tests (NATs) for time to positivity. We va...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Trop Med Hyg
Main Authors: Seilie, Annette M., Chang, Ming, Hanron, Amelia E., Billman, Zachary P., Stone, Brad C., Zhou, Kevin, Olsen, Tayla M., Daza, Glenda, Ortega, Jose, Cruz, Kurtis R., Smith, Nahum, Healy, Sara A., Neal, Jillian, Wallis, Carolyn K., Shelton, Lisa, Mankowski, Tracie (VonGoedert), Wong-Madden, Sharon, Mikolajczak, Sebastian A., Vaughan, Ashley M., Kappe, Stefan H. I., Fishbaugher, Matt, Betz, Will, Kennedy, Mark, Hume, Jen C. C., Talley, Angela K., Hoffman, Stephen L., Chakravarty, Sumana, Sim, B. Kim Lee, Richie, Thomas L., Wald, Anna, Plowe, Christopher V., Lyke, Kirsten E., Adams, Matthew, Fahle, Gary A., Cowan, Elliot P., Duffy, Patrick E., Kublin, James G., Murphy, Sean C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2019
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553913/
https://ncbi.nlm.nih.gov/pubmed/31017084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.19-0094
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados