Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites

Eliminating malaria parasites during the asymptomatic but obligate liver stages (LSs) of infection would stop disease and subsequent transmission. Unfortunately, only a single licensed drug that targets all LSs, Primaquine, is available. Targeting host proteins might significantly expand the reperto...

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Bibliografski detalji
Izdano u:Mol Ther
Glavni autori: Douglass, Alyse N, Kain, Heather S, Abdullahi, Marian, Arang, Nadia, Austin, Laura S, Mikolajczak, Sebastian A, Billman, Zachary P, Hume, Jen C C, Murphy, Sean C, Kappe, Stefan H I, Kaushansky, Alexis
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427874/
https://ncbi.nlm.nih.gov/pubmed/25648263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.18
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