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Malaria parasites target the hepatocyte receptor EphA2 for successful host infection

Invasion of a suitable host hepatocyte by mosquito-transmitted Plasmodium sporozoites is an essential early step in successful malaria parasite infection. Yet, precisely how sporozoites target their host cell and facilitate productive infection remains largely unknown. Here, we found that the hepato...

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Vydáno v:Science
Hlavní autoři: Kaushansky, Alexis, Douglass, Alyse N., Arang, Nadia, Vigdorovich, Vladimir, Dambrauskas, Nicholas, Kain, Heather S., Austin, Laura S., Sather, D. Noah, Kappe, Stefan H.I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783171/
https://ncbi.nlm.nih.gov/pubmed/26612952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad3318
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