Malaria parasites target the hepatocyte receptor EphA2 for successful host infection

Invasion of a suitable host hepatocyte by mosquito-transmitted Plasmodium sporozoites is an essential early step in successful malaria parasite infection. Yet, precisely how sporozoites target their host cell and facilitate productive infection remains largely unknown. Here, we found that the hepato...

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Veröffentlicht in:Science
Hauptverfasser: Kaushansky, Alexis, Douglass, Alyse N., Arang, Nadia, Vigdorovich, Vladimir, Dambrauskas, Nicholas, Kain, Heather S., Austin, Laura S., Sather, D. Noah, Kappe, Stefan H.I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783171/
https://ncbi.nlm.nih.gov/pubmed/26612952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad3318
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