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Susceptibility to Plasmodium liver stage infection is altered by hepatocyte polyploidy

Plasmodium parasites infect hepatocytes of their mammalian hosts and within undergo obligate liver stage development. The specific host cell attributes that are important for liver infection remain largely unknown. Several host signaling pathways are perturbed in infected hepatocytes, some of which...

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Bibliografiske detaljer
Main Authors: Austin, Laura S., Kaushansky, Alexis, Kappe, Stefan H.I.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008336/
https://ncbi.nlm.nih.gov/pubmed/24612025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12282
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