Interrogation of infected hepatocyte signaling reveals that suppression of host p53 is critical for Plasmodium liver stage infection

Plasmodium parasites infect the liver and replicate inside hepatocytes before they invade erythrocytes and trigger clinical malaria. Analysis of host signaling pathways affected by liver stage infection could provide critical insights into host-pathogen interactions and reveal targets for interventi...

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Detalhes bibliográficos
Main Authors: Kaushansky, Alexis, Ye, Albert S., Austin, Laura S., Mikolajczak, Sebastian A., Vaughan, Ashley M., Camargo, Nelly, Metzger, Peter G., Douglass, Alyse N., MacBeath, Gavin, Kappe, Stefan H.I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619000/
https://ncbi.nlm.nih.gov/pubmed/23478020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.02.010
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