Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood

BACKGROUND: Plasmodium 18S rRNA is a biomarker used to monitor blood-stage infections in malaria clinical trials. Plasmodium sporozoites also express this biomarker, and there is conflicting evidence about how long sporozoite-derived 18S rRNA persists in peripheral blood. If present in blood for an...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Murphy, Sean C., Ishizuka, Andrew S., Billman, Zachary P., Olsen, Tayla M., Seilie, Annette M., Chang, Ming, Smith, Nahum, Chuenchob, Vorada, Chakravarty, Sumana, Sim, B. Kim Lee, Kappe, Stefan H. I., Hoffman, Stephen L., Seder, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062992/
https://ncbi.nlm.nih.gov/pubmed/30053881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2422-2
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