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Purification of Plasmodium Sporozoites Enhances Parasite-Specific CD8(+) T Cell Responses

Malaria infection caused by Plasmodium parasites continues to cause enormous morbidity and mortality in areas where it is endemic, and there is no licensed vaccine capable of inducing sterile protection. Hyperimmunization with attenuated whole sporozoites can induce sterile protective immune respons...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Billman, Zachary P., Seilie, Annette M., Murphy, Sean C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962643/
https://ncbi.nlm.nih.gov/pubmed/27217420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01439-15
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