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Purification of Plasmodium Sporozoites Enhances Parasite-Specific CD8(+) T Cell Responses

Malaria infection caused by Plasmodium parasites continues to cause enormous morbidity and mortality in areas where it is endemic, and there is no licensed vaccine capable of inducing sterile protection. Hyperimmunization with attenuated whole sporozoites can induce sterile protective immune respons...

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發表在:Infect Immun
Main Authors: Billman, Zachary P., Seilie, Annette M., Murphy, Sean C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962643/
https://ncbi.nlm.nih.gov/pubmed/27217420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01439-15
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